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Fahrenholz T, Wolle MM, Kingston HMS, Faber S, Kern JC, Pamuku M, Miller L, Chatragadda H, Kogelnik A (2015) Molecular speciated isotope dilution mass spectrometric methods for accurate, reproducible and direct quantification of reduced, oxidized and total glutathione in biological samples

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While cysteine readily oxidizes to form the disulfide cystine, cells contain less cystine than cysteine in the cytosol because the ubiquitous reducing agent, glutathione (which contains cysteine), effectively reverses the formation of cystine by a non-enzymatic reduction reaction

Glutathione is a tripeptide composed of three amino acids: glutamate, cysteine, and glycine

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